The Way Up
Newsletter | |||||
Do we all dance to the beat of a Different Drummer Who happens to be the same? | |||||
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NAMASTE & WELCOME TO THE WAY UP MONTHLY NEWSLETTER! | |||||
Already the year is flying by! I hope you are all off
to the creation of new dreams & REALITIES.
Last month I had the stimulation & pleasure of attending the
6th International Congress on Anti-Aging & Bio-Medical Technologies
sponsored by the American Academy of Anti-Aging Medicine.
It was fascinating to better understand the process of cloning
& to hear from a brilliant man who intends to be the first to clone
himself. He has set up a research center to study cloning as an
alternative for infertile couples. Provocative stuff but let's get on to
what you can use & some of what I found most interesting.
Will give enough scientific detail to make it understandable, but I
hope not tedious & boring. (Let me know on our feedback bar how
heavy or lightweight you want the news to be)
So without further ado:
WHAT'S NEW WITH PROSTATE
CANCER?
In l998 84,500 new cases were diagnosed in the U.S. The
current consensus is that men over 40 years old should have a yearly blood
test for total PSA (prostate specific antigen). A level of 0-4 is
normal; 4-10 is ambiguous (may or may not suggest cancer as can be
elevated by infection, inflammation, & benign prostatic hypertrophy):
over 10 may often suggest cancer.
Those with a PSA over 4 should then have a Free PSA blood
test. This helps differentiate who needs a prostate biopsy.
Those with Free PSA levels greater than 25% need a biopsy & have a
higher risk of cancer. This test helps avoid unneeded biopsies.
WHAT DO PROSTATE & BREAST
CANCER HAVE IN COMMON?
Recent studies suggest that specific by products of the estrogens,
estradiol & estrone may be responsible for both breast & prostate
cancers. These culprits are called 4-catechol estrogens &
estrogen 3,4-quinone.
Yes, men have estrogen too. An unwanted chemical called
aromatase helps to convert testosterone to estradiol. Aromatase
increases with aging, alcohol, obesity, & deficiencies of vitamin C,
zinc & phytochemicals (soy, high-lignan flaxseed oil, black cohosh,
Dong quai, licorice root, & panax ginseng) & excess testosterone
replacement. You may have noticed men with increased breast size if
they are obese or drink too much alcohol. This is related to the
increased estrogen production.
Alcohol plus estrogen replacement therapy & birth control pills
taken by very young women are associated with an increased risk of breast
cancer. A decrease in melatonin, thyroid, progesterone & sex
hormone binding globulins will increase breast & prostate cancer risk.
Now this is not to freak you out about estrogen or hormone
replacement in menopause. There is a practical useful side to this
information.
Remember it is not the estrogen but the unwanted breakdown products
that can be made from certain forms of estrogen that cause the
problem. If enough vitamin B12 & folic acid are present the
4-catechol estrogens will be methylated & safely excreted.
Otherwise pollutants ( & here is one place where the pollution
connection comes in) converts the 4-catechol estrogens to estrogen 3,4
quinone (the other bad one). This then can lead to DNA binding,
mutations, & cancer.
There is more you can do because the amino acid, cysteine,
antioxidants, vitamin E, selenium, zinc, garlic, Vitamin B12, folic acid
& the previously mentioned phytochemicals help to either stop the
formation of these dangerous metabolites or interfere with their negative
impact on DNA.
Natural Progesterone is another help. Many of the steps
leading to estrogen- mediated cancer initiation, promotion &
progression are impeded by natural progesterone. Because progesterone
plays a role in preventing estrogen from converting to 4-catechol
estrogens, it plays a role in protecting against both breast &
prostate cancer. Progesterone has anti-estrogen actions, increases
the elimination of estrogen from the body & down regulates estrogen
receptors.
In studies comparing the application to the breasts of progesterone
cream vs placebo or estrogen cream. The cells in the progesterone
treated breasts had less cell division activity ( hence less stimulation
& possible cancer risk). The dose was 1/4 tsp of progesterone cream
equivalent to 30mg-the same dosage as in our Progonol product or most of
the progesterone creams in health food stores. The estrogen cream
used in the studies increased the rate of cell proliferation in the
breast. Also, applying progesterone cream helps to improve
fibrocystic breasts. The synthetic progesterone such as provera
which is given to most women & is in birth control pills does not have
these beneficial actions.
There is more good news. The potentially problematic
estrogens are the estrone & estradiol, also known as E1 &
E2. There is an E3 called Estriol. It does not convert to the
4-catechol estrogens associated with increased cancer risk. Estriol
is the primary form of estrogen used by Drs who practice alter- natively
& is available from compounding pharmacies. It is usually
combined with lesser amounts of estradiol or both estradiol & estrone
& is known as Biestrogen or Triestrogen. Women who inherently
have higher levels of estriol have a lower risk of breast cancer.
Some compounding pharmacies are listed in out links.
You'll be able to learn more details if you've survived this &
are game for more by reading the soon to be released book by David Zava
PhD on the origins of breast & prostate cancer, the exact title which
is not yet available. He is the cancer researcher who presented this
information at the meeting.
So there are many things we can do to protect ourselves from these
relatively common cancers as we go through life & if you've gotten
this far through this newsletter you are likely proactive in gaining &
securing good health.
You can read more about any of the items mentioned by going to
http://www. thewayup.com Though I could go on & on, you've
probably had enough for now. Please give feedback on what you want to hear
about.
Feel free to forward to anyone you think would be interested &
may you be blessed.
Allowing always the newness, releasing Moving, spiraling to new heights of Universal Participation Until next time Priscilla Slagle M.D. | |||||
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