How do sterols/sterolins work?

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Professor Bouic says, "Sterols and sterolins are literally molecules that help the immune system fight infection. T-cells, the most important part of the immune system, are considered the "maestro" which means they are the controller of the immune system. The sterols and sterolins kick-start the T-cells in order for them to secrete more factors that modulate the infection fighting response."

The two major cell types of the immune system are collectively known as lymphocytes and these consist of the B-cells and the T-cells. When the body encounters antigens, which may be in the form of bacteria, viruses, parasites or other foreign proteins, there is a response mechanism which results in the development of specific T cells. This response mechanism is assisted by a number of chemical mediators known as cytokines, interleukins and lymphokines.

Two of the most important cytokines are Interleukin 2 (IL2) and Interleukin 6 (IL6). Interleukin 2 (IL2) is a T cell growth factor but it also has cytolytic activity in certain specialised T cells (cytotoxic cells) and natural killer cells (NK cells). IL2 is abnormally secreted by cells of patients affected by immune compromised diseases.

Interleukin 6 (IL6) is elevated in the serum of patients with auto immune diseases. It has been found that patients with BPH have elevated IL6 levels in the prostate and this leads to increased binding of testosterone in prostatic tissue.

Gamma interferon (IFN) inhibits viral replication and stimulates the cytotoxic ability of natural killer cells. Natural killer cells are cytotoxic with the major target being virus infected or cancer cells. Sterols and sterolins have a powerful proliferative effect on lymphocytes therefore increasing the production of IL2, gamma interferon (IFN) and natural killer cells. On the other hand sitosterols have an effect similar to DHEA on the body where they inhibit the secretion of IL6 and help mediate the amount of Tumour Necrosis Factor (TNF), which in general is catabolic and pro-inflammatory.

The major benefits therefore of the activity of sterols and sterolins on the immune system is the enhanced function of IL2 and gamma interferon and a decrease in the activity of IL6 and TNF. These functions are immunomodulating and therapeutic in pathologies of immune disorder.

Introduction

What are plant sterols/sterolins?

Is our dietary intake of sterols adequate?

How do sterols/sterolins work?

What are the clinical test results?

How to maintain a healthy immune system

Conclusion

Bibliography

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