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 Coherent therapy

All time as low-intensity laser therapy (LILT) exists, the discussion continues concerning the origin of the therapeutic effect. Laser therapy did not imply, and the physicists could not even dream that the light beam weaker than the light of a pocket flash-lamp an far below the sensitivity threshold would open a new therapy branch and cause a decades-long discussion.

By reviewing the world literature, one may see the progress only in the following: the doubts end whether the laser therapy is only a psychological effect; more and more methods and experimental data appear in the Western literature. The main and the most interesting literature continues to be published in former Communist lands and in Asia. Like 20 years ago, the radiation doses and localisation are being recommended, investigations proceed, experimental data on the effects caused by laser radiation at the levels from atoms to entire organisms are being collected, people continue to wonder how such a tiny energy of laser radiation causes such important systematic changes, while the tens and hundreds of times stronger electromagnetic background surrounding us has no influence at all.

The concept of designing AGNIS L01 laser was quite different. Already a decade ago, we made a conclusion on the basis of experimental data accumulated that the energetic effect of the laser is questionable. As an arbitrary energy flow also brings information, it remained to consider the informational effect. So a superlow-intensity therapeutic laser arose. 5 - 6 years of serial manufacturing, certification and clinical testing in Lithuania, Russia, Bulgaria, Czech have proven the validity of the construction and the device efficiency.

Therefore, we can affirm that the basis of LILT is the informational effect. What is it?

Anyone who interests in the radiation emitted by living beings knows that the man radiates almost the whole range of electromagnetic waves. Localization of a weak illumination surrounding the man, seen by some people and sometimes successfully recorded, is one of the arguments that the organism is surrounded by structured standing fields rather than chaotic radiation. You may recall a picture of lens diffraction rings seen in schoolbooks, which demonstrates how the light damps the light. Another quite familiar analogue is a hologram which forms in the space when the laser beam interacts with the holographic picture elements located in a periodical order on the holographic plate. The holographic pictures are also the result of laser advent. It's the laser again, since only its light is distinguished by one property perhaps not enough evaluated by physicians, namely, the coherence. There are no sources of coherent light in the inorganic nature.

Any laser is a resonator of light particles, or photons. The light beam emitted by it will always be, at least in part, synchronised (coherent) and monochrome (of one colour). These two laser characteristics suffice for us to suppose that even a weakest beam of a therapeutic laser has no natural analogue. This means that the organism is unable to adapt itself and to block this action. The similar situation is with the millimetre waves, or superhigh-frequency (SHF) radiation emitted by therapeutic equipment, where we meet again with inexplicable effect of superlow intensities. The uniqueness of these radiation's, i.e. their coherence, is just the first reason for the efficiency of LIL and SHF therapy.

The second reason lies in the properties of the organism itself. It is known that at the level of biophysical processes the organism is also a synchronised, resonance system. A vast amount of atomic and molecular oscillators in the organism act as a harmonious orchestra, emits the light and maybe just during that emission becomes a perfect self-organising system. The synchronised radiation inevitably creates the standing-field structures both inside and in the nearest surrounding. Maybe, just this is the secret of elusive acupuncture meridians. They reveal themselves only in dynamics. They may be detected by various measurements. They alter chemical and physical properties of tissues. If one acts upon them, the reaction of the whole organism occurs, but then they vanish together with life leaving no anatomical traces. In our age of informatics, when even schoolchildren are able to assess the importance of information exchange in any complicated system, it seems high time to acknowledge the fact that the organism functions not only due to biochemical links. It was recent decade when a number of physicists proposed a holographic model of brain operation which described more adequately the information exchange within it. Perhaps, the field structures surrounding the organism, the acupuncture meridians among them, constitute a separate part of the informational system of the organism operating by holographic principles. Let us remind an amazing feature of a hologram that it can recover the whole picture from its tiniest piece. Does it cause no associations with the ability of the organism to reproduce itself from a single living, that means radiating, cell? There is a suspicion that DNA coils that attract so great attention of genetics are just the smallest oscillator ensembles which, translating in the space, fill the spatial frame of the fields they create.

May it happen that the spatial standing field structures would be the feature that distinguishes between live and dead? You may wonder, why the Nature has created such complicated and barely perceptible informational system of the organism? The answer is quite banal. All other systems of the organism are subjected to natural perturbations: mechanical, temperature, electromagnetic background, and many more other natural factors. Besides, they are energy-consuming, i.e. the organism takes much energy for maintaining these systems. Therefore, the system which operates at the level of biochemical processes would not be able to ensure such self-regulation, stability, and adaptability, which we all observe. Meanwhile, a holographic (or coherent) informational system operating at the level of extremely low-intensity signals appear most resistant to perturbations, because there are no natural coherent radiation's. We do not know up to now any other system which would ensure the observed vitality, adaptability of the organism, and its ability to operate with huge amounts of information. Only when artificial coherent radiation sources arose, we started feeling its presence, because the results of interaction between the two coherent (resonant) systems became evident. Superhigh-capacity memory chips are emerging, the algorithms of parallel information treatment are being designed. Doctors already use successfully the coherent radiation's, but research workers still try to find the interaction mechanisms at the cellular or entire-organism level. But there are only interaction consequences at these levels. Therefore, such ambiguity of the investigation results leads to a conclusion that the research workers treat the problem upside down.

We believe that the essence of the effect of both laser therapy and SHF therapy lies in the interaction between two radiating coherent systems. Another words, two spatial standing-wave structures interact between themselves. The laser beam that is quite coherent delivers the pulse of its "spatial order" to the spatial-field structure of the organism, or to put it differently, synchronizes, reduces the rising chaos of the informational system operation in the organism. The oriental characterisation of a disease as the glow of the perturbed organism then becomes clear. In our case, this means the confusion of the spatial field structure. From this fact the possibility follows to diagnose the features which haven't yet managed to reveal themselves at the physiological level of the organism.

Since the resonance systems interact by extremely low energies, we may predict that the most efficient future therapeutic lasers and SHF therapeutic equipment will radiate only microwatts, but their action will be more purposeful. The possibility to use in medicine the new coherent radiation sources operating in other ranges of electromagnetic waves is also evident. However, the research is blind, because we, due to Oriental medicine, understand only to a minor extent the role of the smallest, though perhaps the most obvious, part of the informational system of the organism. This is the system of acupuncture meridians, which lies until now between belief and rejection for most of the doctors.

The above hypotheses are the basis of AGNIS L01 design. Since many doctors operate it successfully causing the informational effect every day, we believe that these hypothetical assumptions start to become true.

Basing on the above discussion, we may call the low-intensity laser therapy and the SHF therapy by a common title of coherent therapy, since this would reflect more accurately the essence of both methods.

We should note that acknowledging of the existence of the informational system of the organism would take off the mystical halo from the most of the oriental diagnosing and healing methods, various religious rituals. This would allow one to understand the appearance of many new healing techniques, spontaneously but aptly called resonance methods. At the same time, this would be a warning about an entirely new danger level of radiation for the living organism.

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Continuous generation lasers

Since most lasers now used by doctors are the continuous-generation lasers and they are often employed along with pulsed lasers, let us review briefly the fields causing most problems.

As we have mentioned before, the application of continuous generation therapeutic lasers is traditionally reduced to three components of the technique:

  • localization of irradiation;
  • radiation dosage;
  • frequency of healing procedures.

Localisation of irradiation

The localization of irradiation is the characterization of the area where the interaction between radiation and the body should take place. The localization of irradiation is usually presented in pictures or described in words. The acupuncture points and the projections of internal organs to the skin surface are more and more frequently used in laser therapy. Greater differences are seen between author opinions rather than the methodical literature for different types of lasers. It may be assumed that localization of irradiation for all types of lasers is the same, but the attention should be drawn to different depth of bioeffects caused by different kinds of radiation. While the effects caused by continuous-generation lasers are mostly at the surface (particularly for He-Ne lasers), the effect of the pulsed radiation, even at low pulse amplitudes, extends more to deeper tissue layers. Therefore, the doctor possessing and applying both types of lasers should orient himself towards the required penetration depth of the radiation. Comparing the visible and infrared radiation, the higher penetrability of the latter should also be mentioned.

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Laser radiation dosage

The dosage of laser radiation is the amount of laser energy transferred to the tissues during irradiation. This parameter traditionally mentioned in the methodical literature reveals the most significant differences between continuous generation and pulsed lasers. In designing AGNIS pulsed therapeutic lasers, we have taken into account the necessity to exceed the minimal experimentally established dose that already causes the expected effect. Knowing that in reality the doses cannot be estimated accurately (the error often amounts to hundreds of percent), this parameter is not used in AGNIS L01 User's Guide. The pulse amplitude and frequency combinations pointed out here ensure that the lower dose limit is exceeded, and the doctor must not waste his time for unnecessary calculations. As the practical experience shows, even the tiniest radiation doses are more than sufficient, because the doctors get excellent results even by irradiating through dressing and plaster. So the possibility occurs to pay more attention for forming the informational effect by manipulating the pulse and modulation frequencies.

Meanwhile, in the methodical recommendations for continuous generation therapeutic lasers, the radiation dosage is considered as essential. As an example, we present the dosage recommendations for using the He-Ne laser in stomatology [7], because, as may be concluded from literature, the He-Ne lasers are particularly efficient in that branch.

The terms and measuring units used below are as follows:

  • energy is the amount of laser radiation energy measured in joules (J). One joule is the amount of energy given by the power of one watt (W) during one second (s);
  • one joule (J) = 1000 millijoules (mJ);
  • power is the magnitude of radiation energy flux measured in watts;
  • one watt (W) = 1000 milliwatts (mW);
  • radiation dose, or the action energy, is the amount of energy measured in joules (millijoules) obtained by multiplying the laser radiation power (in watts, milliwatts) and the duration of action (exposure) (in seconds);
  • energy density is the ratio between radiation power (in watts, milliwatts) and the irradiated surface area (in square centimeters), which describes the energy concentration in the treated area, measured in mW/cm2, W/cm2.

The energy parameters of the He-Ne lasers most frequently mentioned in the literature are given in Table 3.

    Table 3. Energy parameters of the effects caused by He-Ne lasers
 
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Effect Energy density (mW/cm2) Exposure time (s)
Stimulation of microcirculation 100 - 200 120 - 300
Antiinflammatory effect 100 - 200 120 - 300
Analgesic effect 100 - 200 120 - 300
Activation of metabolic processes in bone tissues 100 120
Stimulation of regeneration 0.1 - 100 30 - 120
Photodynamic effect 100 - 300 60 - 1200
Retardation of cell proliferation 400 - 800 60 - 180
As may be seen from the data presented, the most of the effects should reveal themselves after the tissues absorb tens of joules of radiation energy of continuous generation lasers. On the other hand, most authors applying the continuous generation lasers recommend the radiation doses about 1 J/cm2. The question arises, what is the basis for such reduction of the radiation doses by tens of times? This is a justified step, which will be confirmed by any practising physician, but it wouldn't be logical to question the reliability of the experimental results either. Consequently, here, too, we come across the informational systematic effect that may be apparently caused by the doses of radiation energy tens of times lower than that required for obtaining a particular effect under experimental conditions.

The recommendations in the literature concerning the radiation dosage vary greatly, by tens of times, but most surprisingly, all the techniques are effective. This indicates once more that the energetic effect is of low importance.

By following the classical techniques, we find another source of ambiguity, the dependence of energy density upon the distance between the radiating (defocusing lens or the waveguide end) and irradiated surfaces. When the radiation comes from a spherical source, usual schoolbook laws are valid, i.e. the radiation energy density decreases proportionally to the square of the distance from the source. Meanwhile, within the laser beam the energy is distributed inhomogeneously over the cross-section, the diffraction angle of the beam itself is very small, various diffraction equipment is used, therefore, the decrease of the energy density in the defocused beam with the distance will not be so simple and will depend essentially on the laser design. To know what energy density is, say, at 2 cm from the lens or waveguide end, one should best measure the beam diameter at that point. When IR radiation is used, the advise is to take any dark-imaging device and carry out that measurement.

For those who would like to perform irradiation using the popular 1 J/cm2 dose and for clarity sake, to demonstrate how the radiation power, the irradiated area, energy density, and the exposure time are associated, we present Table 4.

Table 4. The dependence between radiation power, irradiated surface area, energy density, andexposure time
Diameter of irradiated area Laser radiation power (mW)

Radiation energy density (mW/cm2)
Exposure time for the dose of 1 J/cm2 (s)

(mm) 0.5 1 5 10 20 30
1 64
16
128
8
640
1.6
1280
0.8
2560
0.4
3848
0.26
3 7
143
14
71
70
14
141
7
282
3.5
422
2.4
10 0.6
1600
1.3
800
6.4
160
13
80
26
40
38
26
30 0.07
14300
0.14
7100
0.64
1400
1.4
700
0.28
350
0.42
240
100 0.006
160000
0.013
80000
0.064
16000
0.13
8000
0.26
4000
0.38
2600

The table does not take into account the reflection from the skin surface, though it can reduce twice or more the amount of radiation energy transferred to the organism. The reflection coefficient, or the ratio between the reflected and transferred energy, depends upon the skin colour, its moisture, and fatness. If the radiation wavelength changes, the reflection coefficient will be similar to the curves shown in Fig. 1. Therefore, the real exposure time for the radiation dose of 1 J/cm2 would be even longer than that shown in Table 4.

The literature leaves one more question open: if the radiation dose alone causes the therapeutic effect, we must have got identical results after irradiating the area 10 mm in diameter by the 0.5 mW energy flux during 1600 seconds and by the 30 mW flux during 26 seconds. However, we have found no data confirming this conclusion. To the contrary, the recommended exposure times are usually between 1 and 20 minutes. In the literature where radiation dosage parameters are given for both the continuous generation and pulsed lasers, we found such an example: the IR radiation doses of 2.4 J/cm2 for continuous generation and 1 mJ/cm2 for pulsed lasers [2]. It is admitted that from the energetic aspect, the pulsed laser is thousands of times more effective in this case. The situation appears more clear also now if one remembers the informational effect. During the interaction of two resonant systems, at least half a minute is required for mutual adjustment. Therefore, we may claim that there exists a minimal exposure time after which the organism starts to react to the radiation action.

If we learn to recognize in the real timescale the phases of organism reaction to the action of coherent radiation, we would be able to increase the efficiency of the coherent therapy to fantastic limits. The researchers hope to find the solution of this problem in the methods of electropuncture diagnostics.

We believe that the above reasoning proves that there is no sense in radiation dosage using the pulsed laser. When trying to use the methods prepared for continuous generation lasers, as we see, one should reduce the recommended radiation energy doses from 10 to 2000 times. A more exact choice of the dosage is decided by the doctor's intuition.

The number and frequency of healing procedures

In this part of recommendations there is no essential difference between the application of pulsed and continuous generation lasers. Some attention should be possibly drawn to the rhythm and time of the day for the action described in the literature on acupuncture, but taking into account how difficult are these recommendations to be followed in today's life.

For those who would like to avoid indefinite waiting for the first effects after the healing cycles began, we recommend to use any method of electropuncture systematic diagnostics. These methods are able to indicate the variation of the state of the organism even during the irradiation procedure. For that purpose, we fabricate a simply operating indicator of the state of acupuncture points AGNIS BAT 02 based on the Nacatani method adapted by A. Neborskij. The method was used for 15 years in the Russian training centers of cosmonauts.

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