16     When I call a disease a derangement of man's state of health, I am far from wishing thereby to give a hyperphysical explanation of the internal nature of diseases generally, or of any case of disease in particular. It is only intended by this expression to intimate, what it can be proved diseases are not and cannot be, that they are not mechanical or chemical alterations of the material substance of the body, and not dependant on a material morbific substance, but that they are merely spirit-like (conceptual) dynamic derangements of the life.