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Hypervitaminosis A

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Illustrations

Vitamin A source
Vitamin A source

Alternative Names    Return to top

Vitamin A toxicity

Definition    Return to top

Hypervitaminosis means you having too much of a certain vitamin stored in your body. People with hypervitaminosis A have too much vitamin A.

Causes    Return to top

There are two types of vitamin A hypervitaminosis:

In an infant, the sudden intake of too much vitamin A may cause a bulging fontanelle ("soft spot" on the head), and symptoms resembling those of a brain tumor. This group of symptoms is called pseudotumor cerebri and includes a bulging fontanelle, papilledema (swelling of the optic disc), and double vision. Vomiting and drowsiness are common.

The symptoms in adults are less specific. Headache, visual changes, and impaired consciousness suggestive of pseudotumor cerebri may occur. Other symptoms may include nausea, vomiting, dizziness, and blurry vision.

Chronic vitamin A toxicity develops after taking too much vitamin A for long periods. Bone pain and swelling of the bones is common, often associated with high levels of calcium in the blood. Other symptoms include hair loss, high cholesterol, liver damage, and vision problems. Symptoms are often subtle and may include fatigue, malaise, and nausea.

In children, hypervitaminosis A can cause craniotabes (abnormal softening of the skull bones). Irritability, decreased appetite, itchy skin, and poor weight gain are common. There may be skin changes with seborrhea (extremely oily skin and hair), and cracking at the corners of the mouth.

Increased intracranial pressure is seen in both acute and chronic forms.

Symptoms    Return to top

Exams and Tests    Return to top

Treatment    Return to top

Treatment involves simply stopping the use of too much vitamin A.

Outlook (Prognosis)    Return to top

Full recovery is the most likely outcome.

Possible Complications    Return to top

Recent studies show that too much vitamin A taken during pregnancy can cause abnormal development in the fetus. Consult your physician about a proper diet.

When to Contact a Medical Professional    Return to top

Call your health care provider if you think that you or your child may have taken vitamin A in excess or if you have symptoms that may be linked with excess vitamin A.

Prevention    Return to top

To avoid hypervitaminosis A, avoid taking more than the recommended daily allowance of this vitamin. Recent emphasis on vitamin A and beta carotene as anti-cancer vitamins may contribute to chronic hypervitaminosis A, if well-meaning people increase the dosage of vitamins beyond recommended values. More is not always better!

Update Date: 8/8/2006

Updated by: Robert Hurd, MD, Department of Biology, College of Arts and Sciences, Xavier University, Cincinnati, OH. Review provided by VeriMed Healthcare Network

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