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Ovarian overproduction of androgens

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Contents of this page:

Illustrations

Overproductive ovaries
Overproductive ovaries
Follicle development
Follicle development

Definition    Return to top

This condition involves overproduction by the ovaries of hormones (such as testosterone) that stimulate the development of male characteristics.

Causes    Return to top

In healthy women, the ovaries and adrenal glands produce about 40 - 50% of the body's testosterone. Excess androgen production in the ovaries may result from tumors of the ovaries or adrenal glands, polycystic ovarian disease (characterized by enlarged ovaries containing multiple fluid-filled cysts), Cushing's disease (an abnormality in the pituitary gland resulting in excess amounts of corticosteroids, hormones which alter body fat distribution), and congenital adrenal hyperplasia (a group of disorders caused by an enzyme defect during fetal development).

Symptoms    Return to top

Exams and Tests    Return to top

Treatment    Return to top

Treatment depends on the underlying diagnosis causing the increased androgen production. Medications can be given to decrease hair production for patients who have hirsutism or to regulate menstrual cycles. In some cases, surgery may be necessary to remove an ovarian or adrenal tumor.

Outlook (Prognosis)    Return to top

The success of the treatment depends on what caused the excess androgen production. If the condition is caused by an ovarian tumor, surgical removal of the tumor may correct the problem. Most ovarian tumors are benign, and will not recur after surgical removal.

Possible Complications    Return to top

Infertility is a possible complication.

Prevention    Return to top

There is no known prevention.

Update Date: 5/15/2006

Updated by: Melanie N. Smith, M.D., Ph.D., Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA. Review provided by VeriMedHealthcare Network.

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