MedlinePlus Medical Encyclopedia: Translocation

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Translocation

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Illustrations	Definition

Illustrations

Chromosomes and DNA

Definition Return to top

Translocation means a change in location. It usually refers to genetic translocations, in which part of a chromosome is transferred to another chromosome. This type of translocation can result in a bigger, flawed chromosome. In another type of translocation, two chromosomes will trade pieces with each other.

Genetic translocations can cause serious disorders, including chronic myelogenous leukemia.

Update Date: 7/25/2007

Updated by: Chad Haldeman-Englert, MD, Division of Human Genetics, Children's Hospitalof Philadelphia, Philadelphia, PA. Review provided by VeriMed HealthcareNetwork.

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