Mycobacterial culture of bone marrow is a test to determine if tuberculosis or another similar bacteria are present in the bone marrow.

A bone marrow aspiration or biopsy is performed. A sample of bone marrow is placed in culture media specific for tuberculosis and other similar bacteria. It is then examined for growth at routine intervals. Sometimes an acid-fast stain is done initially to help with the diagnosis.

You must sign an informed consent form before the bone marrow biopsy. It is important to remain as still as possible during the test. There is no other special preparation.

The skin over the biopsy or aspiration site (usually the back of the hip or the sternum) will be cleansed. An anesthetic will be injected into the skin surrounding the site to numb the site. Even with the anesthetic, there may be pain or pressure as the bone marrow is removed. The discomfort in the area can last for several days and even weeks.

The test is performed if infection of the bone marrow with tuberculosis or other similar bacteria is suspected.

The bone marrow is normally sterile (no organisms are present).

An infection of the bone marrow with tuberculosis or other similar bacteria. This may also signify disseminated tuberculosis.

There is a slight risk of bleeding or infection from the test.

Not applicable.