Online Etymology Dictionary

experiment (v.): late 15c., from experiment (n.). Intransitive sense by 1787. Related: Experimented; experimenting.
experiment (n.): mid-14c., "action of observing or testing; an observation, test, or trial;" also "piece of evidence or empirical proof; feat of magic or sorcery," from Old French esperment "practical knowledge, cunning; enchantment, magic spell; trial, proof, example; lesson, sign, indication," from Latin experimentum "a trial, test, proof, experiment," noun of action from experiri "to test, try" (see experience (n.)).
experimentation (n.): 1670s, noun of action from experiment (v.).
experimental (adj.): mid 15c., "having experience," from experiment (n.) + -al (1). Meaning "based on experiment" is from 1560s. Meaning "for the sake of experiment" is from 1792.
inexperience (n.): 1590s, from French inexpérience (15c.) or directly from Late Latin inexperientia "inexperience," from in- "not, opposite of" (see in- (1)) + Latin experientia "experimental knowledge; experiment; effort" (see experience (n.)).
empirical (adj.): 1560s, originally in medicine, "pertaining to or derived from experience or experiments," from empiric + -al (1). In a general sense of "guided by mere experience" from 1757. Related: Empirically (1640s as "by means of observation and experiment").
ascertain (v.): early 15c., "to inform, to give assurance," from Anglo-French acerteiner, Old French acertener "to assure, certify" (13c.), from a "to" (see ad-) + certain "sure, assured" (see certain). Modern meaning of "find out for sure by experiment or investigation" is first attested 1794. Related: Ascertained; ascertaining.
simulated (adj.): 1620s, "feigned," past participle adjective from simulate (v.). Meaning "imitative for purposes of experiment or training" is from 1966 (agent noun simulator in the related sense dates from 1947; also see simulation). In commercial jargon, "artificial, imitation" by 1942.
experience (n.): late 14c., "observation as the source of knowledge; actual observation; an event which has affected one," from Old French esperience "experiment, proof, experience" (13c.), from Latin experientia "a trial, proof, experiment; knowledge gained by repeated trials," from experientem (nominative experiens) "experienced, enterprising, active, industrious," present participle of experiri "to try, test," from ex- "out of" (see ex-) + peritus "experienced, tested," from PIE *per-yo-, suffixed form of root *per- (3) "to try, risk" (see peril). Meaning "state of having done something and gotten handy at it" is from late 15c.
probation (n.): early 15c., "trial, experiment, test," from Old French probacion "proof, evidence" (14c., Modern French probation) and directly from Latin probationem (nominative probatio) "approval, assent; a proving, trial, inspection, examination," noun of action from past participle stem of probare "to test" (see prove). Meaning "testing of a person's conduct" (especially as a trial period for membership) is from early 15c.; theological sense first recorded 1520s; criminal justice sense is recorded by 1866. As a verb from 1640s. Related: Probationer; probationary.
simulation (n.): mid-14c., "a false show, false profession," from Old French simulation "pretence" and directly from Latin simulationem (nominative simulatio) "an imitating, feigning, false show, hypocrisy," noun of action from past participle stem of simulare "imitate," from stem of similis "like" (see similar). Meaning "a model or mock-up for purposes of experiment or training" is from 1954.
electricity (n.): 1640s (Browne, from Gilbert's Modern Latin), from electric (q.v.) + -ity. Originally in reference to friction.
Electricity seems destined to play a most important part in the arts and industries. The question of its economical application to some purposes is still unsettled, but experiment has already proved that it will propel a street car better than a gas jet and give more light than a horse. [Ambrose Bierce, "The Cynic's Word Book," 1906]
peril (n.): c. 1200, from Old French peril "danger, risk" (10c.), from Latin periculum "an attempt, trial, experiment; risk, danger," with instrumentive suffix -culum and first element from PIE *peri-tlo-, suffixed form of root *per- (3) "to try, risk" (source also of Latin experiri "to try;" Greek peria "trial, attempt, experience," empeiros "experienced;" Old Irish aire "vigilance;" Gothic ferja "watcher;" Old English fær "danger, calamity"). According to Watkins, this is "A verbal root belonging to the group of" *per- (1) "forward, through" (see per) via the notion of "to lead over, to press forward."
trial (n.): mid-15c., "act or process of testing, a putting to proof by examination, experiment, etc.," from Anglo-French trial, noun formed from triet "to try" (see try (v.)). Sense of "examining and deciding of the issues between parties in a court of law" is first recorded 1570s; extended to any ordeal by 1590s. As an adjectival phrase, trial-and-error is recorded from 1806. Trial balloon (1826) translates French ballon d'essai, a small balloon sent up immediately before a manned ascent to determine the direction and tendency of winds in the upper air, though the earliest use in English is figurative.
guinea pig (n.): rodent native to South America, 1660s. It does not come from Guinea and has nothing to do with the pig. Perhaps so called either because it was brought back to Britain aboard Guinea-men, ships that plied the triangle trade between England, Guinea, and South America [Barnhart, Klein], or from its resemblance to the young of the Guinea-hog "river pig" [OED], or from confusion of Guinea with the South American region of Guyana (but OED is against this). Pig probably for its grunting noises. In the extended sense of "one subjected to an experiment" it is first recorded 1920, because they were commonly used in medical experiments (by 1865).
phreak (n.): 1972, originally in phone phreak, one of a set of technically creative people who electronically hacked or defrauded telephone companies of the day.
The phreaks first appeared on the US scene in the early 1960s, when a group of MIT students were found to have conducted a late night dialling experiment on the Defense Department's secret network. They were rewarded with jobs when they explained their system to Bell investigators. ... The name "phone phreak" identified the enthisiasts with the common underground usage of freak as someone who was cool and used drugs. ["New Scientist," Dec. 13, 1973]
The ph- in phone may have suggested the alteration, and this seems to be the original of the 1990s slang fad for substituting ph- for f- (as in phat).
empiric (adj.): c. 1600, empirical, from Latin empiricus (n.) "a physician guided by experience," from Greek empeirikos "experienced," from empeiria "experience; mere experience or practice without knowledge," especially in medicine, from empeiros "experienced (in a thing), proven by use," from assimilated form of en "in" (see en- (2)) + peira "trial, experiment," from PIE *per-ya-, suffixed form of root *per- (3) "to try, risk" (see peril (n.)). Originally a school of ancient physicians who based their practice on experience rather than theory. Earlier as a noun (1540s) in reference to the sect, and earliest (1520s) in a sense "quack doctor" which was in frequent use 16c.-19c.
ether (n.): late 14c., "upper regions of space," from Old French ether (12c.) and directly from Latin aether "the upper pure, bright air; sky, firmament," from Greek aither "upper air; bright, purer air; the sky" (opposed to aer "the lower air"), from aithein "to burn, shine," from PIE *aidh- "to burn" (see edifice).

In ancient cosmology, the element that filled all space beyond the sphere of the moon, constituting the substance of the stars and planets. Conceived of as a purer form of fire or air, or as a fifth element. From 17c.-19c., it was the scientific word for an assumed "frame of reference" for forces in the universe, perhaps without material properties. The concept was shaken by the Michelson-Morley experiment (1887) and discarded early 20c. after the Theory of Relativity won acceptance, but before it went it gave rise to the colloquial use of ether for "the radio" (1899).

The name also was bestowed c. 1730 (Frobenius; in English by 1757) on a volatile chemical compound known since 14c. for its lightness and lack of color (its anesthetic properties weren't fully established until 1842).
fountain (n.): early 15c., "spring of water that collects in a pool," from Old French fontaine "natural spring" (12c.), from Medieval Latin fontana "fountain, a spring" (source of Spanish and Italian fontana), from post-classical noun use of fem. of Latin fontanus "of a spring," from fons (genitive fontis) "spring (of water)," from PIE root *dhen- (1) "to run, flow" (source also of Sanskrit dhanayati, Old Persian danuvatiy "flows, runs").

The extended sense of "artificial jet of water" (and the structures that make them) is first recorded c. 1500. Hence also fountain-pen (by 1823), so called for the reservoir that supplies a continuous flow of ink. "A French fountain-pen is described in 1658 and Miss Burney used one in 1789" [Weekley]. Fountain of youth, and the story of Ponce de Leon's quest for it, seem to have been introduced in American English by Hawthorne's "Dr. Heidegger's Experiment" (January 1837).
"Did you never hear of the 'Fountain of Youth'?" asked Dr. Heidegger, "which Ponce de Leon, the Spanish adventurer, went in search of two or three centuries ago?"
boll (n.): Old English bolla "bowl, cup, pot," merged with Middle Dutch bolle "round object," borrowed 13c., both from Proto-Germanic *bul-, from PIE *bhel- (2) "to blow, inflate, swell" (see bole). Influenced in meaning by Latin bulla "bubble, ball," ultimately from the same PIE root. Extended c. 1500 to "round seed pod of flax or cotton." Boll weevil is 1895, American English.
In south Texas, among Spanish-speaking people, the insect is generally known as the 'picudo,' a descriptive name which refers to the snout or beak of the insect. English-speaking planters generally referred to the insect at first as 'the sharpshooter,' a term which for many years has been applied to any insect which causes through its punctures the shedding of the squares or the rotting of the bolls. As there are several native insects that are commonly called sharpshooters and which, though injurious, are by no means to be compared with this insect, it becomes necessary to discourage in every way the use of the word sharpshooter as applied to this weevil. The adoption of the term 'Mexican cotton-boll weevil' for the new pest is recommended. [New Mexico College of Agriculture and the Mechanic Arts Agricultural Experiment Station Bulletin No. 19, April 1896]
A case of entomology meddling in etymology.
science (n.): mid-14c., "what is known, knowledge (of something) acquired by study; information;" also "assurance of knowledge, certitude, certainty," from Old French science "knowledge, learning, application; corpus of human knowledge" (12c.), from Latin scientia "knowledge, a knowing; expertness," from sciens (genitive scientis) "intelligent, skilled," present participle of scire "to know," probably originally "to separate one thing from another, to distinguish," related to scindere "to cut, divide," from PIE root *skei- "to cut, to split" (source also of Greek skhizein "to split, rend, cleave," Gothic skaidan, Old English sceadan "to divide, separate;" see shed (v.)).

From late 14c. in English as "book-learning," also "a particular branch of knowledge or of learning;" also "skillfulness, cleverness; craftiness." From c. 1400 as "experiential knowledge;" also "a skill, handicraft; a trade." From late 14c. as "collective human knowledge" (especially "that gained by systematic observation, experiment, and reasoning). Modern (restricted) sense of "body of regular or methodical observations or propositions concerning a particular subject or speculation" is attested from 1725; in 17c.-18c. this concept commonly was called philosophy. Sense of "non-arts studies" is attested from 1670s.
Science, since people must do it, is a socially embedded activity. It progresses by hunch, vision, and intuition. Much of its change through time does not record a closer approach to absolute truth, but the alteration of cultural contexts that influence it so strongly. Facts are not pure and unsullied bits of information; culture also influences what we see and how we see it. Theories, moreover, are not inexorable inductions from facts. The most creative theories are often imaginative visions imposed upon facts; the source of imagination is also strongly cultural. [Stephen Jay Gould, introduction to "The Mismeasure of Man," 1981]

In science you must not talk before you know. In art you must not talk before you do. In literature you must not talk before you think. [John Ruskin, "The Eagle's Nest," 1872]
The distinction is commonly understood as between theoretical truth (Greek episteme) and methods for effecting practical results (tekhne), but science sometimes is used for practical applications and art for applications of skill. To blind (someone) with science "confuse by the use of big words or complex explanations" is attested from 1937, originally noted as a phrase from Australia and New Zealand.