- Ophiuchus
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- constellation (representing Aesculapius), 1650s, from Latin, from Greek ophioukhos, literally "holding a serpent," from ophis "serpent" (see ophio-) + stem of ekhein "to hold, have, keep" (see scheme (n.)). The constellation is equatorial, and Milton's "Ophiuchus huge in th' Arctick Sky" ("Paradise Lost") is a rare lapse for a poet who generally knew his astronomy.