Organon of Medicine § 101 It may easily happen that in the first case of an epidemic disease that presents itself to the physician's notice he does not at once obtain a knowledge of its complete picture, as it is only by a close observation of several cases of every such collective disease that he can become conversant with the totality of its signs and symptoms. The carefully observing physician can, however, from the examination of even the first and second patients, often arrive so nearly at a knowledge of the true state as to have in his mind a characteristic portrait of it, and even to succeed in finding a suitable, homopathically adapted remedy for it. § 102 In the course of writing down the symptoms of several cases of this kind the sketch of the disease picture becomes ever more and more complete, not more spun out and verbose, but more significant (more characteristic), and including more of the peculiarities of this collective disease; on the one hand, the general symptoms (e.g., loss of appetite, sleeplessness, etc.) become precisely defined as to their peculiarities; and on the other, the more marked and special symptoms which are peculiar to but few diseases and of rarer occurrence, at least in the same combination, become prominent and constitute what is characteristic of this malady.89 All those affected with the disease prevailing at a given time have certainly contracted it from one and the same source and hence are suffering from the same disease; but the whole extent of such an epidemic disease and the totality of its symptoms (the knowledge whereof, which is essential for enabling us to choose the most suitable homopathic remedy for this array of symptoms, is obtained by a complete survey of the morbid picture) cannot be learned from one single patient, but is only to be perfectly deduced (abstracted) and ascertained from the sufferings of several patients of different constitutions. § 103 In the same manner as has here been taught relative to the epidemic diseases, which are generally of an acute character, the miasmatic chronic maladies, which, as I have shown, always remain the same in their essential nature, especially the psora, must be investigated, as to the whole sphere of their symptoms, in a much more minute manner than has ever been done before, for in them also one patient only exhibits a portion of their symptoms, a second, a third, and so on, present some other symptoms, which also are but a (dissevered, as it were), portion of the totality of the symptoms which constitute the entire extent of this malady, so that the whole array of the symptoms belonging to such a miasmatic, chronic disease, and especially to the psora, can only be ascertained from the observation of very many single patients affected with such a chronic disease, and without a complete survey and collective picture of these symptoms the medicines capable of curing the whole malady homopathically (to wit, the antipsorics) cannot be discovered; and these medicines are, at the same time, the true remedies of the several patients suffering from such chronic affections. § 104 When the totality of the symptoms that specially mark and distinguish the case of disease or, in other words, when the picture of the disease, whatever be its kind, is once accurately sketched,90 the most difficult part of the task is accomplished. The physician has then the picture of the disease, especially if it be a chronic one, always before him to guide him in his treatment; he can investigate it in all its parts and can pick out the characteristic symptoms, in order to oppose to these, that is to say, to the whole malady itself, a very similar artificial morbific force, in the shape of a homopathically chosen medicinal substance, selected from the lists of symptoms of all the medicines whose pure effects have been ascertained. And when, during the treatment, he wishes to ascertain what has been the effect of the medicine, and what change has taken place in the patient's state, at this fresh examination of the patient he only needs to strike out of the list of the symptoms noted down at the first visit those that have become ameliorated, to mark what still remain, and add any new symptoms that may have supervened. § 105 The second point of the business of a true physician relates to acquiring a knowledge of the instruments intended for the cure of the natural diseases, investigating the pathogenetic power of the medicines, in order, when called on to cure, to be able to select from among them one, from the list of whose symptoms an artificial disease may be constructed, as similar as possible to the totality of the principal symptoms of the natural disease sought to be cured. § 106 The whole pathogenetic effect of the several medicines must be known; that is to say, all the morbid symptoms and alterations in the health that each of them is specially capable of developing in the healthy individual must first have been observed as far as possible before we can hope to be able to find among them, and to select, suitable homopathic remedies for most of the natural diseases. § 107 If, in order to ascertain this, medicines be given to sick persons, only, even though they be administered singly and alone, then little or nothing precise is seen of their true effects, as those peculiar alterations of the health to be expected from the medicine are mixed up with the symptoms of the disease and can seldom be distinctly observed. § 108 There is, therefore, no other possible way in which the peculiar effects of medicines on the health of individuals can be accurately ascertainedthere is no sure, no more natural way of accomplishing this object, than to administer the several medicines experimentally, in moderate doses, to healthy persons, in order to ascertain what changes, symptoms and signs of their influence each individually produces on the health of the body and of the mind; that is to say, what disease elements they are able and tend to produce,91 since, as has been demonstrated (§§ 24-27), all the curative power of medicines lies in this power they possess of changing the state of man's health, and is revealed by observation of the latter. § 109 I was the first that opened up this path, which I have pursued with a perseverance that could only arise and be kept up by a perfect conviction of the great truth, fraught with such blessings to humanity, that it is only by the homopathic employment of medicines92 that the certain cure of human maladies is possible.93 § 110 I saw, moreover, that the morbid lesions which previous authors had observed to result from medicinal substances when taken into the stomach of healthy persons, either in large doses given by mistake or in order to produce death in themselves or others, or under other circumstances, accorded very much with my own observations when experimenting with the same substances on myself and other healthy individuals. These authors give details of what occurred as histories of poisoning and as proofs of the pernicious effects of these powerful substances, chiefly in order to warn others from their use; partly also for the sake of exalting their own skill, when, under the use of the remedies they employed to combat these dangerous accidents, health gradually returned; but partly also, when the persons so affected died under their treatment, in order to seek their own justification in the dangerous character of these substances, which they then termed poisons. None of these observers ever dreamed that the symptoms they recorded merely as proofs of the noxious and poisonous character of these substances were sure revelations of the power of these drugs to extinguish curatively similar symptoms occurring in natural diseases, that these their pathogenetic phenomena were intimations of their homopathic curative action, and that the only possible way to ascertain their medicinal powers is to observe those changes of health medicines are capable of producing in the healthy organism; for the pure, peculiar powers of medicines available for the cure of disease are to be learned neither by any ingenious a priori speculations, nor by the smell, taste or appearance of the drugs, nor by their chemical analysis, nor yet by the employment of several of them at one time in a mixture (prescription) in diseases; it was never suspected that these histories of medicinal diseases would one day furnish the first rudiments of the true, pure materia medica, which from the earliest times until now has consisted solely of false conjectures and fictions of the imaginationthat is to say, did not exist at all.94 § 111 The agreement of my observations on the pure effects of medicines with these older onesalthough they were recorded without reference to any therapeutic objectand the very concordance of these accounts with others of the same kind by different authors must easily convince us that medicinal substances act in the morbid changes they produce in the healthy human body according to fixed, eternal laws of nature, and by virtue of these are enabled to produce certain, reliable disease symptoms each according to its own peculiar character. § 112 In those older prescriptions of the often dangerous effects of medicines ingested in excessively large doses we notice certain states that were produced, not at the commencement, but towards the termination of these sad events, and which were of an exactly opposite nature to those that first appeared. These symptoms, the very reverse of the primary action (§ 63) or proper action of the medicines on the vital force, are the reaction of the vital force of the organism, its secondary action (§§ 62-67), of which, however, there is seldom or hardly ever the least trace from experiments with moderate doses on healthy bodies, and from small doses none whatever. In the homopathic curative operation the living organism reacts from these only so much as is requisite to raise the health again to the normal healthy state (§ 67). § 113 The only exceptions to this are the narcotic medicines. As they, in their primary action, take away sometimes the sensibility and sensation, sometimes the irritability, it frequently happens that in their secondary action, even from moderate experimental doses on healthy bodies, an increased sensibility (and a greater irritability) is observable. § 114 With the exception of these narcotic substances, in experiments with moderate doses of medicine on healthy bodies, we observe only their primary action, i.e., those symptoms wherewith the medicine deranges the health of the human being and develops in him a morbid state of longer or shorter duration. § 115 Among these symptoms, there occur in the case of some medicines not a few which are partially, or under certain conditions, directly opposite to other symptoms that have previously or subsequently appeared, but which are not therefore to be regarded as actual secondary action or the mere reaction of the vital force, but which only represent the alternating state of the various paroxysms of the primary action; they are termed alternating actions. § 116 Some symptoms are produced by the medicines more frequentlythat is to say, in many individuals, others more rarely or in few persons, some only in very few healthy bodies. § 117 To the latter category belong the so-called idiosyncrasies, by which are meant peculiar corporeal constitutions which, although otherwise healthy, possess a disposition to be brought into a more or less morbid state by certain things which seem to produce no impression and no change in many other individuals.95 But this inability to make an impression on every one is only apparent. For as two things are required for the production of these as well as all other morbid alterations in the health of manto wit., the inherent power of the influencing substance, and the capability of the vital force that animates the organism to be influenced by itthe obvious derangements of health in the so-called idiosyncrasies cannot be laid to the account of these peculiar constitutions alone, but they must also be ascribed to these things that produce them, in which must lie the power of making the same impressions on all human bodies, yet in such a manner that but a small number of healthy constitutions have a tendency to allow themselves to be brought into such an obvious morbid condition by them. That these agents do actually make this impression on every healthy body is shown by this, that when employed as remedies they render effectual homopathic service96 to all sick persons for morbid symptoms similar to those they seem to be only capable of producing in so-called idiosyncratic individuals. § 118 Every medicine exhibits peculiar actions on the human frame, which are not produced in exactly the same manner by any other medicinal substance of a different kind.97 § 119 As certainly as every species of plant differs in its external form, mode of life and growth, in its taste and smell from every other species and genus of plant, as certainly as every mineral and salt differs from all others, in its external as well as its internal physical and chemical properties (which alone should have sufficed to prevent any confounding of one with another), so certainly do they all differ and diverge among themselves in their pathogeneticconsequently also in their therapeuticeffects.98 Each of these substances produces alterations in the health of human beings in a peculiar, different, yet determinate manner, so as to preclude the possibility of confounding one with another.99 § 120 Therefore medicines, on which depend man's life and death, disease and health, must be thoroughly and most carefully distinguished from one another, and for this purpose tested by careful, pure experiments on the healthy body for the purpose of ascertaining their powers and real effects, in order to obtain an accurate knowledge of them, and to enable us to avoid any mistake in their employment in diseases, for it is only by correct selection of them that the greatest of all earthly blessings, the health of the body and of the mind, can be rapidly and permanently restored. § 121 In proving medicines to ascertain their effects on the healthy body, it must be borne in mind that the strong, heroic substances, as they are termed, are liable even in small doses to produce changes in the health even of robust persons. Those of milder power must be given for these experiments in more considerable quantities; in order to observe the action of the very weakest, however, the subjects of experiment should be persons free from disease, and who are delicate, irritable and sensitive. § 122 In these experimentson which depends the exactitude of the whole medical art, and the weal of all future generations of mankindno other medicines should be employed except such as are perfectly well known, and of whose purity, genuineness and energy we are thoroughly assured. § 123 Each of these medicines must be taken in a perfectly simple, unadulterated form; the indigenous plants in the form of freshly expressed juice, mixed with a little alcohol to prevent it spoiling; exotic vegetable substances, however, in the form of powder, or tincture prepared with alcohol when they were in the fresh state, and afterwards mingled with a certain proportion of water; salts and gums, however, should be dissolved in water just before being taken. If the plant can only be procured in its dry state, and if its powers are naturally weak, in that case there may be used for the experiment an infusion of it, made by cutting the herb into small pieces and pouring boiling water on it, so as to extract its medicinal parts; immediately after its preparation it must be swallowed whilst still warm, as all expressed vegetable juices and all aqueous infusions of herbs, without the addition of spirit, pass rapidly into fermentation and decomposition, whereby all their medicinal properties are lost. § 124 For these experiments every medicinal substance must be employed quite alone and perfectly pure, without the admixture of any foreign substance, and without taking anything else of a medicinal nature the same day, nor yet on the subsequent days, nor during all the time we wish to observe the effects of the medicine. § 125 During all the time the experiment lasts the diet must be strictly regulated; it should be as much as possible destitute of spices, of a purely nutritious and simple character, green vegetables,100 roots and all salads and herb soups (which, even when most carefully prepared, possess some disturbing medicinal qualities) should be avoided. The drinks are to be those usually partaken of, as little stimulating as possible.101 § 126 The person who is proving the medicine must be pre-eminently trustworthy and conscientious and during the whole time of the experiment avoid all over-exertion of mind and body, all sorts of dissipation and disturbing passions; he should have no urgent business to distract his attention; he must devote himself to careful self-observation and not be disturbed whilst so engaged; his body must be in what is for him a good state of health, and he must possess a sufficient amount of intelligence to be able to express and describe his sensations in accurate terms. § 127 The medicines must be tested on both males and females, in order also to reveal the alterations of the health they produce in the sexual sphere. § 128 The most recent observations have shown that medicinal substances, when taken in their crude state by the experimenter for the purpose of testing their peculiar effects, do not exhibit nearly the full amount of the powers that lie hidden in them which they do when they are taken for the same object in high dilutions potentized by proper trituration and succussion, by which simple operations the powers which in their crude state lay hidden, and as it were dormant, are developed and roused into activity to an incredible extent. In this manner we now find it best to investigate the medicinal powers even of such substances as are deemed weak, and the plan we adopt is to give to the experimenter, on an empty stomach, daily from four to six very small globules of the thirtieth potency of such a substance, moistened with a little water or dissolved in more or less water and thoroughly mixed, and let him continue this for several days. § 129 If the effects that result from such a dose are but slight, a few more globules may be taken daily, until they become more distinct and stronger and the alterations of the health more conspicuous; for not all persons are affected by a medicine in an equally great degree; on the contrary, there is a vast variety in this respect, so that sometimes an apparently weak individual may by scarcely at all affected by moderate doses of a medicine known to be of a powerful character, whilst he is strongly enough acted on by others of a much weaker kind. And, on the other hand, there are very robust persons who experience very considerable morbid symptoms from an apparently mild medicine, and only slight symptoms from stronger drugs. Now, as this cannot be known beforehand, it is advisable to commence in every instance with a small dose of the drug and, where suitable and requisite, to increase the dose more and more from day to day. § 130 If, at the very commencement, the first dose administered shall have been sufficiently strong, this advantage is gained, that the experimenter learns the order of succession of the symptoms and can note down accurately the period at which each occurs, which is very useful in leading to a knowledge of the genius of the medicine, for then the order of the primary actions, as also that of the alternating actions, is observed in the most unambiguous manner. A very moderate dose even, often suffices for the experiment, provided only the experimenter is endowed with sufficiently delicate sensitiveness, and is very attentive to his sensations. The duration of the action of a drug can only be ascertained by a comparison of several experiments. § 131 If, however, in order to ascertain anything at all, the same medicine must be given to the same person to test for several successive days in ever-increasing doses, we thereby learn, no doubt, the various morbid states this medicine is capable of producing in a general manner, but we do not ascertain their order of succession; and the subsequent dose often removes, curatively, some one or other of the symptoms caused by the previous dose, or develops in its stead an opposite state; such symptoms should be enclosed in brackets, to mark their ambiguity, until subsequent purer experiments show whether they are the reaction of the organism and secondary action or an alternating action of this medicine. § 132 But when the object is, without reference to the sequential order of the phenomena and the duration of the action of the drug, only to ascertain the symptoms themselves, especially those of a weak medicinal substance, in that case the preferable course to pursue is to give it for several successive days, increasing the dose every day. In this manner the action of an unknown medicine, even of the mildest nature, will be revealed, especially if tested on sensitive persons. § 133 On experiencing any particular sensation from the medicine, it is useful, indeed necessary, in order to determine the exact character of the symptom, to assume various positions while it lasts, and to observe whether, by moving the part affected, by walking in the room or the open air, by standing, sitting or lying the symptom is increased, diminished or removed, and whether it returns on again assuming the position in which it was first observed,whether it is altered by eating or drinking, or by any other condition, or by speaking, coughing, sneezing or any other action of the body, and at the same time to note at what time of the day or night it usually occurs in the most marked manner, whereby what is peculiar to and characteristic of each symptom will become apparent. § 134 All external influences, and more especially medicines, possess the property of producing in the health of the living organism a particular kind of alteration peculiar to themselves; but all the symptoms peculiar to a medicine do not appear in one person, nor all at once, nor in the same experiment, but some occur in one person chiefly at one time, others again during a second or third trail; in another person some other symptoms appear, but in such a manner that probably some of the phenomena are observed in the fourth, eighth or tenth person which had already appeared in the second, sixth or ninth person, and so forth; moreover, they may not recur at the same hour. § 135 The whole of the elements of disease a medicine is capable of producing can only be brought to anything like completeness by numerous observations on suitable persons of both sexes and of various constitutions. We can only be assured that a medicine has been thoroughly proved in regard to the morbid states it can producethat is to say, in regard to its pure powers of altering the health of manwhen subsequent experimenters can notice little of a novel character from its action, and almost always only the same symptoms as had been already observed by others. § 136 Although, as has been said, a medicine, on being proved on healthy subjects cannot develop in one person all the alterations of health it is capable of causing, but can only do this when given to many different individuals, varying in their corporeal and mental constitution, yet the tendency to excite all these symptoms in every human being exists in it (§ 117), according to an eternal and immutable law of nature, by virtue of which all its effects, even those that are but rarely developed in the healthy person, are brought into operation in the case of every individual if administered to him when he is in a morbid state presenting similar symptoms; it then, even in the smallest dose, being homopathically selected, silently produces in the patient an artificial state closely resembling the natural disease, which rapidly and permanently (homopathically) frees and cures him of his original malady. § 137 The more moderate, within certain limits, the doses of the medicine used for such experiments areprovided we endeavor to facilitate the observation by the selection of a person who is a lover of truth, temperate in all respects, of delicate feelings, and who can direct the most minute attention to his sensationsso much the more distinctly are the primary effects developed, and only these, which are most worth knowing, occur without any admixture of secondary effects or reactions of the vital force. When, however, excessively large doses are used there occur at the same time not only a number of secondary effects among the symptoms, but the primary effects developed, and only these, which are most worth knowing, occur without any admixture of secondary effects or reactions of the vital force. When, however, excessively large doses are used there occur at the same time not only a number of secondary effects among the symptoms, but the primary effects also come on in such hurried confusion and with such impetuosity that nothing can be accurately observed; let alone the danger attending them, which no one who has any regard for his fellow-creatures, and who looks on the meanest of mankind as his brother, will deem an indifferent manner. § 138 All the sufferings, accidents and changes of the health of the experimenter during the action of a medicine (provided the above conditions [§§ 124-127] essential to a good and pure experiment are complied with) are solely derived from this medicine, and must be regarded and registered as belonging peculiarly to this medicine, as symptoms of this medicine, even though the experimenter had observed, a considerable time previously, the spontaneous occurrence of similar phenomena in himself. The reappearance of these during the trial of the medicine only shows that this individual is by virtue of his peculiar constitution, particularly disposed to have such symptoms excited in him. In this case they are the effect of the medicine; the symptoms do not arise spontaneously while the medicine that has been taken is exercising an influence over the health of the whole system, but are produced by the medicine. § 139 When the physician does not make the trial of the medicine on himself, but gives it to another person, the latter must note down distinctly the sensations, sufferings, accidents and changes of health he experiences at the time of their occurrence, mentioning the time after the ingestion of the drug when each symptom arose and, if it lasts long, the period of its duration. The physician looks over the report in the presence of the experimenter immediately after the experiment is concluded, or if the trial lasts several days he does this every day, in order, whilst everything is still fresh in his memory, to question him about the exact nature of every one of these circumstances, and to write down the more precise details so elicited, or to make such alterations as the experimenter may suggest.102 § 140 If the person cannot write, the physician must be informed by him every day of what has occurred to him, and how it took place. What is noted down as authentic information on this point, however, must be chiefly the voluntary narration of the person who makes the experiment, nothing conjectural and as little as possible derived from answers to leading questions should be admitted; everything must be ascertained with the same caution as I have counselled above (§§ 84-99) for the investigation of the phenomena and for tracing the picture of natural diseases. § 141 But the best provings of the pure effects of simple medicines in altering the human health, and of the artificial diseases and symptoms they are capable of developing in the healthy individual, are those which the healthy, unprejudiced and sensitive physician institutes on himself with all the caution and care here enjoined. He knows with the greatest certainty the things he has experienced in his own person.103 § 142 But how some symptoms104 of the simple medicine employed for a curative purpose can be distinguished amongst the symptoms of the original malady, even in diseases, especially in those of a chronic character that usually remain unaltered, is a subject appertaining to the higher art of judgement, and must be left exclusively to masters in observation. § 143 If we have thus tested on the healthy individual a considerable number of simple medicines and carefully and faithfully registered all the disease elements and symptoms they are capable of developing as artificial disease-producers, then only have we a true materia medicaa collection of real, pure, reliable105 modes of action of simple medicinal substances, a volume of the book of nature, wherein is recorded a considerable array of the peculiar changes of the health and symptoms ascertained to belong to each of the powerful medicines, as they were revealed to the attention of the observer, in which the likeness of the (homopathic) disease elements of many natural diseases to be hereafter cured by them are present, which, in a word, contain artificial morbid states, that furnish for the similar natural morbid states the only true, homopathic, that is to say, specific, therapeutic instruments for effecting their certain and permanent cure. § 144 From such a materia medica everything that is conjectural, all that is mere assertion or imaginary should be strictly excluded; everything should be the pure language of nature carefully and honestly interrogated. § 145 Of a truth, it is only by a very considerable store of medicines accurately known in respect of these their pure modes of action in altering the health of man that we can be placed in a position to discover a homopathic remedy, a suitable artificial (curative) morbific analogue for each of the infinitely numerous morbid states in nature, for every malady in the world.106 In the meantime, even nowthanks to the truthful character of the symptoms, and to the abundance of disease elements which every one of the powerful medicinal substances has already shown in its action on the healthy bodybut few disease remain, for which a tolerably suitable homopathic remedy may not be met with among those now proved as to their pure action,107 which without much disturbance, restores health in a gentle, sure and permanent mannerinfinitely more surely and safely than can be effected by all the general and special therapeutics of the old allopathic medical art with its unknown composite remedies, which do but alter and aggravate but cannot cure chronic diseases, and rather retard than promote recovery from acute diseases and frequently endanger life. § 146 The third point of the business of a true physician relates to the judicious employment of the artificial morbific agents (medicines) that have been proved on healthy individuals to ascertain their pure action, in order to effect the homopathic cure of natural diseases. § 147 Whichever of these medicines that have been investigated as to their power of altering man's health we find to contain in the symptoms observed from its use the greatest similarity to the totality of the symptoms of a given natural disease, this medicine will and must be the most suitable, the most certain homopathic remedy for the disease; in it is found the specific remedy of this case of disease.
§ 148
The natural disease is never to be considered as a noxious material
situated somewhere within the interior or exterior of man (§ 11-13) but as one produced by an inimical
spirit-like (conceptual) agency which, like a kind of infection (note to
§ 11) disturbs
in its instinctive existence of the spirit-like (conceptual) principle of
life within the organism torturing it as an evil spirit and compelling it
to produce certain ailments and disorders in the regular course of its
life. These are known as symptoms (disease). If, now, the influence of this
inimical agency that not only caused but strives to continue this disorder,
be taken away as is done when the physician administers an artificial
potency, capable of altering the life principle in the most similar manner
(a homopathic medicine) which exceeds in energy even in the smallest
dose the similar natural disease (§§ 33, 279), then the influence of the
original noxious morbid agent on the life principle is lost during the
action of this stronger similar artificial disease. Thence the evil no
longer exists for the life principleit is destroyed. If, as has been
said, the selected homopathic remedy is administered properly, then
the acute natural disease which is to be overruled if recently developed,
will disappear unperceptibly in a few hours. § 149 Diseases of long standing (and especially such as are of a complicated character) require for their cure a proportionately longer time. More especially do the chronic medicinal dyscrasia so often produced by allopathic bungling along with the natural disease left uncured by it, require a much longer time for their recovery; often, indeed, are they incurable, in consequence of the shameful robbery of the patient's strength and juices (venesections, purgatives, etc.), on account of long continued use of large doses of violently acting remedies given on the basis of empty, false theories for alleged usefulness in cases of disease appearing similar, also in prescribing unsuitable mineral baths, etc., the principal feat performed by allopathy in its so-called methods of treatment. § 150 If a patient complain of one or more trivial symptoms, that have been only observed a short time previously, the physician should not regard this as a fully developed disease that requires serious medical aid. A slight alteration in the diet and regimen will usually suffice to dispel such an indisposition.
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