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ADENINE , or 6-AMINO-See also:PURIN, C5H5N5, in See also:chemistry, a basic substance which has been obtained as a decomposition product of nuclein, and also from the pancreatic glands of oxen. It has been synthesized by E. See also:Fischer (Berichte, 1897, 30, p. 2238) by See also:heating 2.6.8-trichlorpurin with to times its See also:weight of See also:ammonia for six See also:hours at roo° C.; by this means 6-amino-2.8-dichlorpurin is obtained, which on reduction by means of hydriodic See also:acid and phosphonium iodide is converted into adenine. In 1898 E. Fischer also obtained it from 8-oxy-2.6-dichlorpurin ,Berichte, 1898, 31, p. 104). It crystallizes in See also:long needles; forms salts C5H5N5.2HI and (C5H5N5)2.HsSO4.2H20, and is converted by nitrous acid into hypoxanthine or 6-oxypurin. On heating with hydrochloric acid at 18o-2oo° C. it is decomposed; the products of the reaction being glycocoll, ammonia, formic acid and See also:carbon dioxide. Various methyl derivatives of adenine have been described by E. Fischer (Berichte, 1898, 31, p. 104) and by M. See also:Kruger (Zeit. See also:fur physiol. Chemie, 1894, 18, p. 434). For the constitution of adenine see PURIN. Additional information and CommentsThere are no comments yet for this article.
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