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Moses

masc. proper name, name of the Hebrew prophet and lawgiver, Middle English Moises, from Latin, from Greek Mouses, from Hebrew Mosheh, which is of unknown origin.

Most scholars see in it the Hebraization of Egyptian mes, mesu 'child, son,' which is often used in theophorous names. According to this derivation the words of Pharaoh's daughter in Ex. 2:10, 'For out of the water I drew him' are not the explanation of the Hebrew name Mosheh, but express the idea that the Egyptian name given by Pharaoh's daughter resembles in sound, and therefore, reminds us of, the Hebrew verb mashah 'he drew out,' which is suggestive of the words spoken by Pharaoh's daughter. [Ernest Klein, "A Comprehensive Etymological Dictionary of the English Language"]

As an expletive or oath, Oh, Moses, 1840; Holy Moses is attested by 1877.

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Definitions of Moses from WordNet

Moses (n.)
(Old Testament) the Hebrew prophet who led the Israelites from Egypt across the Red sea on a journey known as the Exodus; Moses received the Ten Commandments from God on Mount Sinai;
Moses (n.)
United States painter of colorful and primitive rural scenes (1860-1961);
Synonyms: Grandma Moses / Anna Mary Robertson Moses
From wordnet.princeton.edu