"great period of revival of classical-based art and learning in Europe that began in the fourteenth century," 1840, from French renaissance des lettres, from Old French renaissance, literally "rebirth," usually in a spiritual sense, from renastre "grow anew" (of plants), "be reborn" (Modern French renaître), from Vulgar Latin *renascere, from Latin renasci "be born again, rise again, reappear, be renewed," from re- "again" (see re-) + nasci "be born" (Old Latin gnasci, from PIE root *gene- "give birth, beget").
An earlier term for it was revival of learning (1785). In general usage, with a lower-case r-, "a revival" of anything that has long been in decay or disuse (especially of learning, literature, art), it is attested from 1872. Renaissance man is first recorded 1906.