late 15c., "intertwined, past-participle adjective from twist (v.). Meaning "perverted, mentally strange" (1900) probably is from twist (n.) in a sense of "mental peculiarity, perversion" attested by 1811.
many of the facts seemed twisted out of any semblance to reality
Twinkie
twinkle
twirl
twirler
twist
twisted
twister
twist-off
twisty
twit
twitch