c. 1500, "act of adulterating; state of being debased by mixture with something else," generally of inferior quality, from Latin adulterationem (nominative adulteratio) "an adulteration, sophistication," noun of action from past-participle stem of adulterare "corrupt, falsify; debauch; commit adultery," from ad "to" (see ad-) + alterare "to alter" (see alter), though Watkins explains it as ad alterum "(approaching) another (unlawfully)." Meaning "a result of adulterating" is from 1650s.