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aggravation (n.)

late 15c., "an increasing in gravity or seriousness," from Middle French aggravation, from Late Latin aggravationem (nominative aggravatio), noun of action from past-participle stem of Latin aggravare "make heavier," figuratively "to embarrass further, increase in oppressiveness," from ad "to" (see ad-) + gravare "weigh down," from gravis "heavy" (from PIE root *gwere- (1) "heavy"). Sense of "irritation" is from 1610s.

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Definitions of aggravation from WordNet

aggravation (n.)
an exasperated feeling of annoyance;
Synonyms: exasperation
aggravation (n.)
unfriendly behavior that causes anger or resentment;
Synonyms: irritation / provocation
aggravation (n.)
action that makes a problem or a disease (or its symptoms) worse;
the aggravation of her condition resulted from lack of care
Synonyms: exacerbation
From wordnet.princeton.edu