late 15c., "an increasing in gravity or seriousness," from Middle French aggravation, from Late Latin aggravationem (nominative aggravatio), noun of action from past-participle stem of Latin aggravare "make heavier," figuratively "to embarrass further, increase in oppressiveness," from ad "to" (see ad-) + gravare "weigh down," from gravis "heavy" (from PIE root *gwere- (1) "heavy"). Sense of "irritation" is from 1610s.
the aggravation of her condition resulted from lack of care
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