1610s, "a cutting off of tree branches, a pruning," also "operation of cutting off a limb, etc., of a body," from Middle French amputation or directly from Latin amputationem (nominative amputatio), noun of action from past-participle stem of amputare "to cut off, lop off; cut around, to prune," from am(bi)- "around" (from PIE root *ambhi- "around") + putare "to prune, trim" (from PIE root *pau- (2) "to cut, strike, stamp").