"opposite, unlike, averse," 1811, in a translation of Swedenborg; see antipathy + -ic. Perhaps modeled on French antipathique. In later use it tends to be a medical word for "producing contrary symptoms," in place of antipathetic.
antinomy
Antioch
antioxidant
antipasto
antipathetic
antipathic
antipathy
anti-perspirant
antiphon
antiphonal
antiphony