1610s, "involving apoplexy," from French apoplectique (16c.), from Latin apoplecticus, from Greek apoplektikos "disabled by a stroke, crippled, struck dumb, senseless; crippled, palsied," extended form of apoplektos, verbal adjective of apoplessein "strike down and incapacitate" (see apoplexy). Meaning "showing symptoms of apoplexy" (1721) gradually shaded into "enraged, very angry" by early 19c. Noun meaning "one suffering apoplexy" is from 1660s.