c. 1400, arce-hoole; see arse + hole (n.). In Old English, Latin anus was glossed with earsðerl, literally "arse-thrill," with thrill (n.) in its original sense of "hole" (compare nostril).
arrow
arrow-head
arrow-root
arroyo
arse
arsehole
arsenal
arsenic
arseward
arson
arsonist