"make rough," 1650s, from Latin asperatus, past participle of asperare "to roughen, make rough," figuratively "exasperate," from asper "rough" (see asperity). Related: Asperated; asperating.
asparagus
aspartame
Aspasia
aspect
aspen
asperate
asperation
Asperger's Syndrome
asperges
asperity
asperse