1530s, "action of breathing into," from Latin aspirationem (nominative aspiratio) "a breathing on, a blowing upon; rough breathing; influence," noun of action from past-participle stem of aspirare "strive for, seek to reach," literally "breathe at, blow upon" (see aspire). Meaning "steadfast longing for a higher goal, earnest desire for something above one" is recorded from c. 1600 (sometimes collectively, as aspirations).