asthenia (n.)

"weakness, debility," 1788, medical Latin, from Greek astheneia "want of strength, weakness, feebleness, sickness; a sickness, a disease," from asthenes "weak, without strength, feeble," from a- "not, without" (see a- (3)) + sthenos "strength, power, ability, might," which is of uncertain origin, perhaps from PIE root *segh- "to have, hold," on the notion of "steadfastness, toughness."