"a wasting away through lack of nourishment," 1610s (atrophied is from 1590s), from French atrophie, from Late Latin atrophia, from Greek atrophia "a wasting away," abstract noun from atrophos "ill-fed, un-nourished," from a- "not, without" (see a- (3)) + trophe "nourishment," from trephein "to fatten" (see -trophy).