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callous (adj.)

c. 1400, "hardened," in the physical sense, from Latin callosus "thick-skinned," from callus, callum "hard skin" (see callus). The figurative sense of "unfeeling, hardened in the mind" appeared in English by 1670s. Related: Callously; callousness.

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Definitions of callous from WordNet
1
callous (adj.)
emotionally hardened;
a callous indifference to suffering
Synonyms: indurate / pachydermatous
callous (adj.)
having calluses; having skin made tough and thick through wear;
calloused skin
with a workman's callous hands
Synonyms: calloused / thickened
2
callous (v.)
make insensitive or callous; deaden feelings or morals;
Synonyms: cauterize / cauterise
From wordnet.princeton.edu