"fine, excellent, going well," 1919, but it may have origins in 19c. U.S. Southern black speech. Origin unknown; suspects include Latin, Yiddish (Hebrew kol b'seder), Italian, Louisiana French (coupe-sétique), and Native American. Among linguists, none is considered especially convincing.
his smile said that everything was copacetic
cootie
cooties
co-owner
cop
cop out
copacetic
copasetic
cope
copeck
Copenhagen
Copernicus