1650s, "outer shell, husk;" in botany, zoology, anatomy, "some part or structure resembling bark or rind," from Latin cortex "bark of a tree, "from PIE root *sker- (1) "to cut." Specifically of the brain, by 1741.
corset
corsetier
Corsica
cortege
Cortes
cortex
cortical
cortico-
corticoid
corticole
corticosteroid