1550s, "a pull exerting the utmost effort (of a horse), from dead (adj.) + lift (n.). From 1560s in figurative sense of "a position in which one can do no more;" by 1882 as "an effort involving the whole strength."
Dead Sea
deadbeat
dead-center
deaden
Deadhead
dead-lift
deadline
deadlock
deadly
dead-march
deadness