early 15c., debilitacioun, "physical weakness, state of being enfeebled," from French débilitation (13c.) and directly from Latin debilitationem (nominative debilitatio) "a laming, crippling, weakening," noun of action from past-participle stem of debilitare "to weaken," from debilis "weak, helpless," from de "from, away" (see de-) + -bilis "strength," from PIE root *bel- "strong" (see Bolshevik). From 1520s as "action of rendering weak."