1530s, "to lop off, take away or deduct a part of," from Medieval Latin defalcatus, past participle of defalcare, from de "off, away" (see de-) + Latin falx, falcem "sickle, scythe, pruning hook" (see falcate). Modern scientific use dates from 1808.
deerskin
de-escalate
def
deface
defacement
defalcate
defalcation
defamation
defamatory
defame
defatigable