1670s, "explosion accompanied by loud sound," from French détonation, from Medieval Latin detonationem (nominative detonatio), from Latin detonare "to thunder down, to release one's thunder, roar out," from de "down" (see de-) + tonare "to thunder" (see thunder (n.)). Sense of "act of causing to explode" (mid-18c.) developed in French.
detestable
detestation
dethrone
dethronement
detonate
detonation
detonator
detour
detox
detoxicate
detoxification