1640s, "right as opposed to left," from Medieval Latin dexteralis "on the right," from Latin dexter "right, opposite of left," from PIE root *deks-. From 1871 as "right-handed." By 1818 in reference to univalve shells, "having the aperture on the right side when held upright in front of the observer with the apex upward." Related: Dextrally; dextrality.