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enervate (v.)

c. 1600, "deprive of force or strength," from Latin enervatus, past participle of enervare "to weaken" (see enervation). Literal sense of "to weaken, impair" in English is from 1610s. Related: Ennervated; ennervating. As a verb Middle English had enerve (c. 1400, eneruyd).

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Definitions of enervate from WordNet

enervate (v.)
weaken mentally or morally;
enervate (v.)
disturb the composure of;
Synonyms: faze / unnerve / unsettle
From wordnet.princeton.edu