"act of making satisfaction or reparation for an offense, atonement, reparation," early 15c., expiacioun, from Latin expiationem (nominative expiatio) "satisfaction, atonement," noun of action from past-participle stem of expiare "make amends for, atone for; purge by sacrifice, make good," from ex- "completely" (see ex-) + piare "propitiate, appease," from pius "faithful, loyal, devout" (see pious).
The sacrifice of expiation is that which tendeth to appease the wrath of God. [Thomas Norton, translation of Calvin's "Institutes of Christian Religion," 1561]