1670s, "cultivation of a garden," coined from Latin hortus "garden" (from PIE root *gher- (1) "to grasp, enclose"), probably on model of agriculture. Famously punned upon by Dorothy Parker.
horsy
hortative
hortatory
Hortense
horticultural
horticulture
horticulturist
Horus
hosanna
hose
Hosea