1550s, whobub "confused noise," of uncertain origin; according to OED generally believed to be of Irish origin, perhaps from Gaelic ub!, expression of aversion or contempt, or Old Irish battle cry abu, from buide "victory."
HUAC
hub
hubba-hubba
Hubble
hub-bub
hubbub
hubby
hubcap
Hubert
hubris
hubristic