early 15c., "to forbid, prohibit," back-formation from inhibition or else from Latin inhibitus, past participle of inhibere "to hold in, hold back, keep back," from in- "in, on" (from PIE root *en "in") + habere "to hold" (from PIE root *ghabh- "to give or receive"). Psychological sense (1876) is from earlier, softened meaning of "restrain, check, hinder" (1530s). Related: Inhibited; inhibiting.