late 14c., "a break of continuity," from Latin interruptionem (nominative interruptio) "a breaking off, interruption, interval," noun of action from past participle stem of interrumpere "to break apart, break off" (see interrupt (v.)). Meaning "a breaking in upon some action" is from c. 1400; that of "a pause, a temporary cessation" is early 15c.
the telephone is an annoying interruption
interrogation
interrogative
interrogator
interrogatory
interrupt
interruption
intersect
intersection
intersex
interspace
interspecific