mid-15c., "to poison" (obsolete), from Medieval Latin intoxicatus, past participle of intoxicare "to poison," from in- "in" (from PIE root *en "in") + Latin toxicare "to poison," from toxicum "poison" (see toxic). Meaning "make drunk" first recorded 1570s (implied in intoxicated). Figurative sense "excite to a high pitch of feeling" is attested from 1590s. Related: Intoxicating.
intolerant
intonate
intonation
intone
intoxicant
intoxicate
intoxicated
intoxication
intra-
intra-cellular
intractability