c. 1200, "last, final," superlative of late. From 1590s as "most recent." As a noun, 1520s, "the last in order." Colloquial the latest "the news" attested from 1886. At the latest "at the most distant date" is from 1884.
the very latest scientific discoveries
have you heard the latest?
laterality
Lateran
latero-
latescent
latesome
latest
latex
lath
lathe
lather
Latian