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left-handed (adj.)

late 14c., of persons, "having the left hand stronger or more capable than the right;" 1650s of tools, etc., "designed for use with the left hand," from left (adj.) + -handed. In 15c. it also could mean "maimed." Sense of "underhanded" is from early 17c., as in left-handed compliment (1787, also attested 1855 in pugilism slang for "a punch with the left fist"), as is that of "illicit" (as in left-handed marriage, for which see morganatic; 17c. slang left-handed wife "concubine"). Related: Left-handedly; left-handedness.

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Definitions of left-handed from WordNet
1
left-handed (adj.)
(of marriages) illicit or informal;
in Colonial America left-handed marriages between Frenchmen and Indians were frequent
left-handed (adj.)
(of marriages) of a marriage between one of royal or noble birth and one of lower rank; valid but with the understanding that the rank of the inferior remains unchanged and offspring do not succeed to titles or property of the superior;
Synonyms: morganatic
left-handed (adj.)
rotating to the left;
Synonyms: levorotary / levorotatory
left-handed (adj.)
ironically ambiguous;
a left-handed compliment
left-handed (adj.)
lacking physical movement skills, especially with the hands; "could scarcely empty a scuttle of ashes, so handless was the poor creature"- Mary H. Vorse;
Synonyms: bumbling / bungling / butterfingered / ham-fisted / ham-handed / handless / heavy-handed
2
LEFT-HANDED (adj.)
using or intended for the left hand;
left-handed golfers need left-handed clubs
left-handed scissors
From wordnet.princeton.edu