1640s, "action or power of motion," from Latin loco "from a place" (ablative of locus "a place;" see locus) + motionem (nominative motio) "motion, a moving" (see motion (n.)). From 1788 as "movement from place to place."
lock-up
loco
loco-
loco-foco
locomote
locomotion
locomotive
locomotor
loco-weed
locum-tenens
locus