1816, in literal sense "of or pertaining to physical manipulation," from manipulate + -ive. In the sense of "tending to manage by mental influence," especially for one's own purposes, by 1909. Related: Manipulatively; manipulativeness.
the early manipulative techniques of a three-year-old child
manilla
manioc
manipulable
manipulate
manipulation
manipulative
manipulator
Manitoba
manitou
man-killer
mankind