"unnecessary, indiscriminate killing of human beings," sometimes also applied to wholesale slaughter of animals, 1580s, from Middle French massacre "wholesale slaughter, carnage," from Old French macacre, macecle "slaughterhouse; butchery, slaughter," which is of unknown origin; perhaps related to Latin macellum "provisions store, butcher shop," which probably is related to mactāre "to kill, slaughter."