"a metropolis; a very large, heavily populated urban complex," 1832, from Greek megas (genitive megalou) "great" (see mickle) + polis "city" (see polis). The word was used in classical times as an epithet of great cities (Athens, Syracuse, Alexandria), and it also was the name of a former city in Arcadia. Related: Megalopolitan.
megalo-
megalocardia
megalomania
megalomaniac
megalomaniacal
megalopolis
megaphone
megapixel
Megara
megaspore
megatherium