"having a bad or ugly shape, crippled, deformed, monstrous," also "degraded, perverted," late 14c., from mis- (1) "badly, wrongly" + old alternative past participle of shape (v.). The verb misshape (1520s) is perhaps a back-formation.
misshapen old fingers
misrepresentation
misrule
miss
missal
missel
misshapen
missile
missing
mission
missionary
Mississippi