1520s, "omit to do or perform;" 1530s, "treat carelessly or heedlessly, treat with disrespect or without proper attention or care;" from Latin neglectus, past participle of neglegere "to make light of, disregard, be indifferent to, not heed, not trouble oneself about," literally "not to pick up," variant of neclegere, from Old Latin nec "not" (from PIE root *ne- "not") + legere "pick up, select," from PIE root *leg- (1) "to collect, gather." Related: Neglected; neglecting.