"an opening, a mouth or aperture," early 15c., from Old French orifice "the opening of a wound" (14c.) and directly from Late Latin orificium "an opening," literally "mouth-making," from Latin os (genitive oris) "mouth" (see oral) + combining form of facere "to make, do" (from PIE root *dhe- "to set, put"). Related: Orificial.
the orifice into the aorta from the lower left chamber of the heart
Orientalism
orientate
orientation
oriented
orienteering
orifice
oriflamme
origami
origin
original
originality