early 15c., palpitacioun, "rapid movement, trembling or quivering motion," from Latin palpitationem (nominative palpitatio), noun of action from past-participle stem of palpitare "to throb, to flutter, to tremble, to quiver," frequentative of palpare "touch gently, stroke; wheedle, coax" (see palpable). Specifically of unnatural rapid beating or pulsation of the heart (excited by emotion, disease, etc.) by c. 1600.